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1 Introduction Gastrointestinal diseases are highly prevalent worldwide and account for a significant portion of global disease burden (1) and healthcare costs (2)

Plated cells were pretreated with 4 L of agonist, or antagonist (Ex 9-39 (GLP-1R antagonist) or BIIE0246 (Y2-R antagonist)), at a given target concentration and incubated for 20 min before performing the assay

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HSV infection, however, induces early ROS production and NF-B and IRF-3 pathways, resulting in type I IFN and interferon-stimulated gene production 22

6 The use of GLP-1RAs is also associated with a lower risk of adverse cardiac events, such as myocardial infarction and stroke

Known side effects of semaglutide include gastrointestinal issues, nausea, and hypoglycemia