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Lancet 2006;368:1696-1705

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Cerebrolysin Primary uses: Stroke recovery Traumatic brain injury Dementia and Alzheimer's support Cognitive enhancement Typical dosing: 5-10ml daily or every other day Duration: 10-30 injections per course Administration: Intramuscular injection (preferred) or slow IV infusion Special notes: Mixture of neuropeptides from porcine brain Used clinically in Europe and Asia Strong evidence for neurological recovery Prescription medication in many countries Dihexa Primary uses: Cognitive enhancement Memory improvement Potential Alzheimer's treatment Typical dosing: 5-10mg daily Injectable or oral (both available) Duration: Cycles of 4-8 weeks Administration: Subcutaneous injection or oral Special notes: Extremely powerful nootropic (7 orders of magnitude more potent than BDNF) Research stage (not FDA-approved) Limited human data Use with caution N-Acetyl Semax Amidate Primary uses: Advanced cognitive enhancement Neuroprotection Focus and mental clarity Typical dosing: 300-600mcg daily Intranasal or injectable Duration: 2-4 weeks, then break Administration: Intranasal spray (preferred) or subcutaneous Special notes: More potent than regular Semax Longer-lasting effects Excellent for demanding cognitive work Skin and cosmetic peptides (injectable) These improve skin quality beyond topical application

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Standalone B12 is appropriate for vegans, older adults, those with pernicious anaemia or malabsorption disorders, people taking metformin or proton pump inhibitors, and anyone with confirmed B12 deficiency on blood tests

Acting as a co-factor for several antioxidant enzymes