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In the cerebral cortex of animals after occlusion of the carotid arteries, the concentration of HSP70 was higher than in the control group after 12 h and after 1 day, after 4 days the protein concentration decreased but was at the level or higher than in the control group ( Experimental studies for different periods of ischemia (1 h, 6 h, 24 h, 48 h, 72 h, 120 h, and 21 days) found that during the period of the greatest ischemic damages 2472 h, hyperproduction of lactate is observed, during the inhibition of GK enzyme that catalyzes the first reaction of glycolysis

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Preconditioning exercise inhibits neuron ferroptosis and ameliorates brain ischemia damage by skeletal muscle-derived exosomes via regulating miR-484/ACSL4 axis

The efficacy of probucol combined with hydration in preventing contrast-induced nephropathy in patients with coronary heart disease undergoing percutaneous coronary intervention: a multicenter, prospective, randomized controlled study