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Study design The Phase 2 trial was a randomized, double-blind, placebo-controlled study that enrolled 338 adults with obesity (BMI 30 or higher) or overweight (BMI 27 or higher) with at least one weight-related condition

In the context of patients with MASLD and diabetes, only one clinical study evaluated the benefits of beinaglutide treatment over 24 weeks compared to recommended standard lifestyle management for T2DM

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This tri agonist architecture allows researchers to investigate how simultaneous activation of incretin and glucagon pathways alters intracellular signaling processes such as cyclic AMP generation, kinase activation, and coordinated metabolic pathway regulation across tissues