It does this by converting a hydroxyl group into a methoxy group
The study, which tested the drug in 529 patients with obesity and heart failure with preserved ejection fraction (HFpEF), demonstrated a 16.6-point increase at 52 weeks, with regard to the Clinical Summary Score (CSS) on the Kansas City Cardiomyopathy Questionnaire (KCCQ) a measure of symptoms of heart failure in comparison to an 8.7-point increase in the placebo group
Accessed 12 Feb 2018
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While IV therapy is highly effective because it delivers the antioxidant directly into the bloodstream, bypassing the digestive tract entirely, it is also expensive, invasive, and impractical for daily, long-term management