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Preventive cardiologist Neha Pagidipati, MD (Duke University School of Medicine, Durham, NC), called SOUL an important clinical trial because it confirms the cardiovascular benefits of oral semaglutide hinted at in PIONEER-6, giving clinicians and patients confidence that the drug works as well as the injectable formulation
Retatrutide works by mimicking several of these hormones
The compound remains at preclinical stages [14]
Both are GLP-1 receptor agonists given as weekly injections
Open dialogue with insurers demystifies the treatment plan and manages expectations
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