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In the reference group, subjects fasted overnight for at least 6 h before oral semaglutide dosing with 120 mL water
GLP-1 specifically binds to the glucagon-like peptide-1 receptor (GLP-1R) in the body, directly stimulating the secretion of insulin by pancreatic -cells, promoting proliferation and differentiation, and inhibiting cell apoptosis, thereby exerting a glycemic lowering effect
Ilyas A, Wijayasinghe YS, Khan I, el Samaloty NM, Adnan M, Dar TA, Poddar NK, Singh LR, Sharma H, Khan S
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