[109] Four of the six coordination sites are provided by the corrin ring and a fifth by a dimethylbenzimidazole group
By blocking NNMT, 5-Amino-1MQ restores NAD+ availability in fat cells, shifting their behavior toward fat mobilization and oxidation rather than storage
In diet-induced obese (DIO) mouse models, 5-Amino-1MQ treatment produced significant reductions in body weight, white adipose tissue mass, and adipocyte cell size without significant effects on food intake suggesting a metabolic rather than appetite-suppressing mechanism
Supply shortages have been a recurring issue since the compound gained popularity, though manufacturing has been scaling to meet demand
So, there is no risk of overdose
This peptide is for research use only.