Phase 3 trials were not initiated, and the compound does not hold any approved fat loss indication
Pain or Irritation at the Injection Site One of the most common side effects is mild discomfort or irritation at the site of the injection
This pharmacokinetic design became the template for later incretin peptides
A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)
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When combined with diet and exercise, patients often report increased energy and improved weight-loss results