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Current protocols recommend treating patients with an initial dose of 150 mg/kg NAC, infused over a period of an hour, upon hospitalization, followed by decreasing amounts of NAC infused over the next 20 hours[1]

Chem Biol Interact 322:108968

The compound is synthesized using solid-phase peptide synthesis and purified to analytical standards suitable for controlled biochemical experimentation

Cagrilintide Reconstitution Math Cagrilintide - dose per draw at common vial sizes Vial Size 5 mg BAC Water 2.0 mL Concentration 2.5 mg/mL 0.25 mg 0.10 mL (10 units) 0.5 mg 0.20 mL (20 units) 1.0 mg 0.40 mL (40 units) 2.4 mg 0.96 mL (96 units) Vial Size 10 mg BAC Water 2.0 mL Concentration 5.0 mg/mL 0.25 mg 0.05 mL (5 units) 0.5 mg 0.10 mL (10 units) 1.0 mg 0.20 mL (20 units) 2.4 mg 0.48 mL (48 units) Vial Size 10 mg BAC Water 1.0 mL Concentration 10.0 mg/mL 0.25 mg 0.025 mL (2.5 units) 0.5 mg 0.05 mL (5 units) 1.0 mg 0.10 mL (10 units) 2.4 mg 0.24 mL (24 units) Cagrilintide is sensitive - inject BAC water down the vial wall and swirl gently

Physician familiarity with the original molecules will matter a lot when biosimilars start entering the market

Patients should avoid direct contact between ice packs and medication pens, as this may cause freezing