The key milestones are as follows: The FDA granted orforglipron the Commissioner's National Priority Review Voucher, a designation that could compress the standard 10-12 month review period to as little as 1-2 months
GLP-1 is released by the gut after eating, and it helps to regulate blood sugar levels and appetite
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring peptide encoded within mitochondrial DNA the powerhouses of your cells
These bacteria have been shown to aid the secretion of p9 as well as metabolise fibre that we eat (which is why getting your 30g a day is important) into beneficial short-chain fatty acids
Groop P-H, Thomas MC, Moran JL, et al
Notably, OPA1 expression in remission samples showed the most pronounced downregulation across various factors compared to diagnostic and relapsed AML samples (Fig