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True migraine (throbbing, one-sided, with nausea and light sensitivity) is different from positional headache (dull, bilateral, position-dependent)
1 of the ESM)
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Nothe 28-day expiration is mandatory regardless of visual appearance
This is why some researchers start with a 3mg vial for the early phases and switch to 5mg or 10mg vials once they reach higher doses where the consumption rate matches the expiration timeline better
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