doi: 10.3389/fnut.2022.853058 Received 12 January 2022 Accepted 11 February 2022 Published 14 March 2022 Volume 9 - 2022 Edited by Anna Maria Giudetti, University of Salento, Italy Reviewed by Stefan Kabisch, Charit Universittsmedizin Berlin, Germany
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All such work is conducted under research-use-only conditions
Compared with those in normal skin fibroblast subpopulations, the expression levels of senescence- and inflammation-associated genes, including p16 (also known as CDKN2A ), SFRP4 18 , IGF1 19 , and IL1R1 were increased in keloid mesenchymal fibroblasts, whereas CCND2 , IL-6 , CXCL3 , and IL1R1 were increased in keloid pro-inflammatory fibroblasts (Fig
2007, Harris et al
As for DCF, some parameters were added in order to describe OMZ specific association and degradation rate constants, while all other parameters were considered not to differ between DEM, DCF or OMZ treatment