Patients with a personal history of pancreatitis should generally abstain from alcohol, as both the medication and alcohol independently increase pancreatitis risk, and the combination may pose unacceptable risk
Looking ahead, the key strategies for product innovation and differentiation are likely to focus on five main directions: expanding the therapeutic indications, achieving precision treatment with multiple biological targets, optimizing the clinical application of drug combinations, developing new formulations of oral medications, and extending the duration of drug action
Semaglutide, by contrast, was approved in 2017 as the first long-acting GLP-1 agonist
Zhu G, Chang X, Kang Y, Zhao X, Tang X, Ma C, et al
This is significant because many patients on tirzepatide dose escalation schedules end up at higher doses that cost more on other platforms
Various resources are available to help reduce costs, such as the Patient Assistance Program (PAP), and savings offers available for uninsured or self-pay individuals