However, it is not difficult to obtain L-carnitine from food
Therefore, this review hypothesizes that mitochondria serve as central hubs regulating oxidative stress, inflammation, and aging, and their dysfunction contributes to various diseases, including cancers, cardiovascular diseases, neurodegenerative disorders, metabolic diseases, sepsis, ocular pathologies, liver diseases, and autoimmune conditions
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We also highlight various novel drugs, small molecules, and materials that have been applied in preclinical studies to target ferroptosis in various diseases and used in relevant disease models
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Ferroptosis-IN-23 inhibits ferroptosis in zebrafish, alleviates neuronal apoptosis , ROS accumulation, and dopaminergic neuron damage in a zebrafish model of Parkinson's disease