Oxidative stress damages peptides just as it damages collagen and other proteins
L-Glutathione (GSH) is a thiol-containing tripeptide that acts directly as an antioxidant, neutralizing reactive oxygen species, free radicals, peroxides, and lipid peroxides
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doi: 10.1186/1472-6793-11-12 54 YamadaCYamadaYTsukiyamaKYamadaKUdagawaNTakahashiNet al
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We believe that this limited contribution and non-essentiality of caspase-3 for the execution of eryptosis is associated with the absence of the upstream mitochondrial pathways in mature erythrocytes linked with the expulsion of this particular organelle at the terminal stages of erythropoiesis, as well as downstream effectors