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Nat Rev Endocrinol 19(4):201216

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The study one of seven trials planned found orforglipron is just as safe as other GLP-1 drugs, with the similar side effects like diarrhea and nausea

Instead, it significantly increases resting basal metabolic rate , accelerates hepatic fat decomposition, and promotes oxidation and consumption of white fat

Deficiency Causes In humans, severe vitamin E deficiency rarely occurs from inadequate -tocopherol intake but has been observed as a result of malnutrition (24)