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10.3390/molecules28062834 53 YangY.LiuY.WangY.ChaoY.ZhangJ.JiaY.et al (2022)

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It includes a 4-6 week loading phase (higher doses, typically twice weekly), followed by a 4-6 week maintenance phase (lower doses, typically once weekly), then a 4-8 week off period before considering another cycle

This often overlaps with individuals who are also addressing hormonal decline, metabolic slowdown, and other changes associated with getting older