Ciotti M, Marrone A, Potter C, Owens IS
The breakdown happens in tissues through normal metabolic pathways, not in a single organ, which is why clearance takes time
Injectable Semaglutide has not been evaluated by the FDA, but side effects are expected to be similar to other Semaglutide-based medications reviewed by the FDA, which have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar), flatulence (gas buildup), gastroenteritis (an intestinal infection), and gastroesophageal reflux disease (a type of digestive disorder)
Likewise, in preclinical models, GIP-GLP-1 co-agonist has also showed the same phenomena in mice [56]
The peptides for brain health category is expanding, and semaglutide growing evidence base in neuroprotection positions it as a molecule of particular interest for cognitive research
Reduced appetite, which is a therapeutic effect, not a side effect