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Both stimulate fibroblast proliferation and extracellular matrix production

This selective action suggests sophisticated regulatory effects rather than simple stimulation of all smooth muscle tissue

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There were no differences in circulating concentrations of MMP-9 ( p = 0.697), MPO ( p = 0.544), TIMP-1 ( p = 0.252), nor TIMP-2 ( p = 0.971) between PTSD participants with ( n = 13) and without ( n = 12) a history of mTBI

If cholesterol hypersecretion occurs, the gallbladder bile will become consistently supersaturated with cholesterol [23], a potent condition predisposing to precipitation and aggregation of cholesterol crystals [24]

So, it is important to protect existing elastin fibers from environmental stressors