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This epigenetic modulation promotes BDNF transcriptional activation in the hippocampus and striatum [157, 158]

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Evaluating the efficacy of the treatment with benfotiamine and alpha-lipoic acid in distal symmetric painful diabetic polyneuropathy

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Furthermore, it significantly decreased aldosterone concentrations, a known predictor of increased cardiovascular mortality risk, which would indicate AT1R blockade ( Finally, the prevalence of primary aldosteronism (PA), the most common form of secondary hypertension, is reported to be 11-14% in patients with diabetes and hypertension

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