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GLP-1s are medical treatments, not cosmetic shortcuts, and are comparable to bariatric surgery in their medical purpose
This is common, especially in the first six to eight weeks of titration, and it typically improves as your body adjusts to the medication
These effects could be particularly valuable in treating conditions such as inflammatory bowel disease, where mucosal healing is a critical therapeutic endpoint
A Phase 2 randomised controlled trial published in the New England Journal of Medicine (Jastreboff et al., 2023) reported mean placebo-adjusted weight reductions of up to approximately 24% over 48 weeks in adults with obesity
The authors describe this as the first study of its kind and say randomised trials are needed to confirm whether GLP-1 medications meaningfully change fibromyalgia symptoms
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