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The reason the who should avoid list is framed so broadly is not boilerplate caution

Some people experience less nausea and cramping with oral semaglutide compared to injections because absorption is slower and more gradual, though both formulations work through the same GLP-1 pathway

Rather than targeting a specific substance, the drugs may be affecting the craving itself

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Tanning of the skin, when given as a shot under the skin