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In simple terms, the observed cosmetic changes (fewer wrinkles, tighter skin, stronger hair) match what GHK-Cus biology would predict

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These changes weaken the tendon structure and create the pain and dysfunction that patients experience

Additionally, performing control experiments with GST alone (without the fusion protein) can help identify and account for any non-specific binding

The neurological symptoms can be particularly concerning

Liposomal glutathione is encapsulated within lipid structures, which changes how it is processed