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The SUSTAIN 6 trial showed that subcutaneous semaglutide reduced major adverse cardiovascular events by 26% in patients with type 2 diabetes and established cardiovascular disease (hazard ratio 0.74, 95% CI 0.58-0.95)
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Ferroptosis activation in TGF--treated HK-2 cells is suppressed by GPX4 overexpression
For more on side-effect management, see our semaglutide nausea relief guide
Interestingly, in clinical trials for 2.4 mg semaglutide, only 0.2% of 407 participants reported a burning sensation, which highlights the importance of proper injection technique
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