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General symptoms of thiamine deficiency include confusion, psychomotor retardation, impaired memory and cognitive function, and ataxia (36, 40)

You'll need to take vitamin B12 injections depending on your situation if your deficiency is not diet-related

Like GLP-1 S, its effect is appetite- and metabolism-driven rather than a direct action on adipose tissue, which keeps it mechanistically separate from AOD-9604 despite both being discussed in fat-loss research contexts

This is a concern that applies to all significant weight loss interventions, not just tirzepatide, but it becomes more relevant as the magnitude of weight loss increases

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As energy stabilizes, workouts may feel more manageable and consistency with nutrition often becomes easier