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At the molecular level, the mRNA expressions of all the three genes ( Star, Cyp11a1, and Hsd17b3 ) significantly dropped in the MSG group compared with the control and sham groups

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GLP-1s and kidney function have a complicated relationship

Studies show that discontinuing GLP-1 therapy after achieving weight loss often results in weight regain, making long-term consistent dosing essential for sustained results

Orforglipron (brand name: Foundayo), a once-daily pill-based weight-loss drug that targets the same GLP-1 system as Wegovy, has recently been approved by the US Food and Drug Administration for treating obesity