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(Mechanism of Action) Janumet works through two distinct, non-overlapping pathways that complement each other to maintain glycemic homeostasis

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Studies have shown that it inhibits the mRNA and protein expression of CYP1A2, CYP2D6 and CYP3A4 (Ooi et al., 2011)

Goal: Support metabolic efficiency through NNMT inhibition, potentially enhancing fat oxidation and NAD+ levels

Recent advances and structure-activity relationship studies of DPP-4 inhibitors as anti-diabetic agents

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