Many patients with rheumatoid arthritis and psoriatic arthritis and other conditions live with overweight and obesity
When ROS levels exceed those of antioxidant defenses, there is an aberrant increase in free radical generation resulting in mitochondrial damage and leading to oxidative stress and subsequently this increased stress can reduce ETC activity (Gu et al., 2013) (Figure 2)
& Imaizumi, T
Explore tissue repair peptides for comprehensive mechanism understanding
You can message your provider, report your symptoms, and get guidance on whether to stay the course or adjust your dose immediately
Alternative treatments include SGLT2 inhibitors (dapagliflozin, empagliflozin), DPP-4 inhibitors (sitagliptin), metformin, sulfonylureas, or insulin therapy