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Our group has also identified several protective molecules against BBB damage induced by glycation and oxidative stress [72], inflammation [73] and excitotoxicity [74]
IFN- also shows better outcomes in patients with COVID-19 ARDS (George et al., 2020) based on its effect of blocking viral replication and promoting humoral and cellular immune responses (Lokugamage et al., 2020)
194 GLP-1 also acts directly on the liver, inhibiting glycogenolysis, promoting glycogen synthesis, and regulating the expression of lipid metabolism-associated genes, thereby reducing hepatic fat accumulation and improving glucose and lipid homeostasis along the gutliver axis
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It mimics the natural hormone amylin, which is co-secreted with insulin and plays a key role in promoting satiety, slowing gastric emptying, and modulating food intake
