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The combination of these peptides creates a multi-layered regenerative network in which gene regulation, cytoskeletal dynamics, vascular support, matrix remodeling, and inflammation control converge

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Applying a pro-remodeling signal during an active remodeling window is the intuitive appeal, and it mirrors the logic behind combining growth-factor or peptide serums with needling in clinical practice

On the other hand, considering the short distance between the C atom of cystathionine and the C4 atom of PLP in the cystathionine-bound external aldimine, the C hydrogen may directly move to the C4 atom without a base

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