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Chronic high-dose pyridoxine can cause sensory neuropathymanifesting as numbness, tingling, or gait instabilityemphasizing the need for appropriate dosing and periodic reassessment
This makes it a strong option for those dealing with gut inflammation, poor nutrient absorption, or digestive discomfort that has not responded to conventional approaches
A 2020 study published in Regulatory Toxicology and Pharmacology found BPC-157 well-tolerated with no severe toxic effects across multiple animal species, supporting its safety profile for continued research
Two major B12-dependent pathways matter most for neuropathy
