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Key Takeaways Retatrutide reduced liver fat by 81-86% at higher doses (8mg and 12mg) in a 48-week phase 2 trial

Semaglutide reduces glucagon levels, which helps to lower blood sugar

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Wegovy can cause nausea, especially during dose increases

*Correspondence: Agata Blazewicz, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The stomach area often responds quickly, with a reduction in visceral and subcutaneous fat. These hormone-sensitive areas can be hard to manage with exercise alone, but semaglutide helps mobilize stored fat here too