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Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence
It is associated with ageing, inflammation and can affect all aspects of health and wellbeing
The starting reference models for each dataset were either the previously determined cryo-EM structure of PV3-SC8 from a plant expression system 18 (EMDB accession code EMD-3747) low-pass filtered to 60 to avoid bias for PV3-SC8 GPP3+GSH and PV3-SC8 pleconaril+GSH or for wt PV2-CP17 a 50 low-pass filtered model was generated from a prior reconstruction of a subset of the data
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