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HERA 48 was performed by seeding HMEC-1-FcRn cells (1.5 10 5 cells/well) to a Costar 48-well TC-Treated Multiple Well Plate (Corning) in complete culture medium (250 L/well) for approximately 2024 h until confluent

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TZP treatment was correlated with reduced systolic blood pressure (SBP), waist circumference, plasma lipid concentrations and fasting insulin (103)

Structure and mechanism of bloodbrain-barrier lipid transporter MFSD2A

The result is higher inner-ear concentration and longer retention of drugs compared to systemic administration, as demonstrated by the optical tracer studies