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Liver-specific expression of carboxylesterase 1g/esterase-x reduces hepatic steatosis, counteracts dyslipidemia and improves insulin signaling
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upregulation of collagen, elastin, decorin, and glycosaminoglycan synthesis
There is also good alignment in the structures of the Cagri C-terminal residues and those of sCT in complex with AMY 1 R, and of the RAMP1 and CTR ECDs and the interface between them, when aligned by the CTR protomer ECD (Fig