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Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic cells

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The activity half-life in rat of exendin-4 in fusion with a carrier antibody has been previously reported as 10.8 h 26 , which is similar to the 11.5 h value we observed in mice for exendin-4 in fusion with the anti-PCSK9 Ab#2 antibody (Supplementary Table 4)

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