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The lower promoter methylation of GPX1, a member of the GPX family that interact with oxidative stress, results in high expression levels of GPX1 in some cancer cell lines (Wei R
Human COP1 plays a key role in the ubiquitination of a wide range of transcriptional regulators, including p53, c-Jun, and members of the ETS, and C/EBP families 20,25,26,27,28,29
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However, data in PD populations are Limited and heterogeneous
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