Contact your GP, study team, or supervising clinician if fatigue: Is severe enough to significantly impair daily functioning, work, or personal care Persists without any improvement despite the dose stabilising Is accompanied by dizziness, fainting, or palpitations , which may suggest dehydration or electrolyte disturbance Occurs alongside unexplained weight loss beyond expected levels , pallor, or breathlessness which could indicate nutritional anaemia Is associated with low mood, persistent sadness, or loss of motivation , as these may suggest depression rather than drug-related tiredness Develops alongside jaundice, dark urine, or abdominal pain , which warrant urgent assessment to exclude hepatic or pancreatic causes Seek urgent medical attention (call 999 or go to A&E) if you experience: Severe, persistent upper abdominal pain, particularly if it radiates to the back and is accompanied by vomiting these are potential symptoms of pancreatitis and require immediate assessment [12] Chest pain, severe dizziness, confusion, or an inability to keep any fluids down For urgent advice that does not require emergency services , contact NHS 111 (online at 111.nhs.uk or by telephone)

These technologies enable the system to process extensive patient data, constructing precise cancer progression models while effectively distinguishing between affected and healthy individuals
Combining it with B12 might enhance these effects
The type or types of treatment(s) and number of treatments you need will be the major cost influences
They address the most common causes
Mid-morning snack: Greek yogurt (3/4 cup) with a drizzle of honey and crushed almonds