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The approval of Wegovy, a weight loss drug that contains a higher dose of semaglutide, by the US Food and Drug Administration and European Medicines Agency, also appears to have added pressure on global supply chains

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This creates what some clinicians describe as built-in accountability the medication effectively discourages high-fat eating through immediate, uncomfortable consequences

For our patients with type 2 diabetes, Tirzepatide offers dual benefits: effective blood glucose management and a potential reduction in body weight, which can play a critical role in improving overall health outcomes

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Vockley (University of Pittsburgh, PA, USA) for critical review of the manuscript