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doi: 10.3390/ani14081193 51 WangN.WangC.QiM.LinX.ZhaA.TanB.et al

PMID: 6478442

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Tirzepatide, a dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist, exhibits favourable effects on pancreatic -cells and hepatic steatosis in obese type 2 diabetic db/db mice

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The optimization of mitochondrial function and structure is consistent with the common mechanism by which GLP-1RAs improve sarcopenia by increasing mitochondrial area and quantity, and optimizing their morphology [36]