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The results showed that TGFB2 expression increased after HG induction, while Ex4 treatment decreased TGFB2 expression ( TGFB2 reverses the protective effect of exendin-4 on DR It was reported that transforming TGFB2 was involved in the pathogenic process of DR
T.ShenX.et al (2021)
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Excess iron can drive oxidative stress , essentially creating internal "rust", which damages cells, contributes to inflammation, and ironically impairs detoxification
Wong JHEP Reports .2026
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