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MDMA is widely known as Ecstasy, although street formulations may contain additional drugs such as methamphetamine, ketamine, cocaine, dextromethorphan, ephedrine, or caffeine, making its effects unpredictable

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In practical terms, a 95 kg person with 30% body fat who maintains a 400-calorie daily deficit might lose 5-6 kg total over 12 weeks through diet alone

Patients who have had gastric banding may have more flexibility since the stomach remains intact, though medication passage is still restricted through a narrow band