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These alterations promote systemic low-grade inflammation through an imbalance between elevated pro-inflammatory cytokines (e.g., IL-6, TNF-) and anti-inflammatory mediators (e.g., IL-10) (267269)
10.3389/fpls.2017.01457 107 MartinoiaE.GrillE.TommasiniR.KreuzK.AmrheinN
Possible side effects include injection-site reactions, temporary skin irritation from topical use, and in rare cases, the "copper uglies" phenomenon
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Agitation and aggression are also common NPS in AD
If a breastfeeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA
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