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Mutant levels of A1298C are also high, with up to 10 percent of the population having two copies of this mutation (x)

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J Clin Invest 134:e172889 Hendershot CS, Bremmer MP, Paladino MB et al (2025) Once-Weekly semaglutide in adults with alcohol use disorder: A randomized clinical trial

Nguyen JT et al

A person with anorexia nervosa will experience significant weight loss due to food restriction and starvation together with an intense fear of gaining weight

For healthy patients used short-term, it has an acceptable safety profile but it lacks the cardiovascular protection that semaglutide provides