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TB-500 provides complementary anti-inflammatory activity through multiple mechanisms including direct inhibition of NF-B signaling, modulation of immune cell phenotypes, and promotion of inflammatory resolution
Guo C, Lu H, Gao W, Wang L, Lu K, Wu S, Pataer A, Huang M, El-Zein R, Lin T, Roth JA, Mehran R, Hofstetter W, Swisher SG , Wu X, Fang B
The lower dose (100 mg vs 500 mg in standard reduced products) reflects the theoretically higher bioavailability of the acetylated form
2022;44(5):736-743 e3
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