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Moreover, the dose-dependent effect of HLA-DR2 haplotypes on MS susceptibility suggests a potential link between genetic factors and disease manifestation [153]

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The 3DMM approach integrates information of several experimental conditions and replicates into one stoichiometry model, which uses phosphopeptide-, non-phosphorylated peptide- and corresponding protein-intensities from any multiplexed quantification method

Treatment durations can range from a few weeks to several months, depending on the desired results