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A supplement is nothing more than the sum of its parts
Several transcription factors such as activator protein (AP-1), nuclear factor kappa B (NF-B), and predominantly the nuclear factor erythroid 2related factor 2 (Nrf2) are involved in the induction of antioxidant enzymes
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By combining these treatments, individuals may experience complementary benefits that enhance their physical and psychological health
Fitaro injection may cause side effects like allergic reactions, pancreatitis, gall stones, cholecystitis, hypoglycemia, acute kidney injury, retinal damage, thyroid cancer, fatigue, headache, rash, alopecia, vitreous haemorrhage in patients with diabetic retinopathy, anxiety, dizziness, and discomfort and redness at the injection site
On the other hand, TIMP-2 plays an opposite role to MMP-2 by inhibiting the protease activity in tissues undergoing remodeling of the ECM (Edelstein, 2017), thus a balance between MMP-2 and TIMP-2 plays a key role in maintaining the proper development and metabolism of the ECM
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