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This process is essential for sustaining physical activity, supporting heart health, and promoting muscle recovery

GLP-1 receptor agonists mimic a natural hormone called glucagon-like peptide-1

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To explore through an alternative strategy whether GLP-1R binding kinetics influence PM recycling and insulin secretion, we utilized the GLP-1R allosteric modulator 4-(3-( b enzyloxy)phenyl)-2-( e thylsulfinyl)-6-( t rifluoro-methyl) p yrimidine (BETP), which alters the residence time of orthosteric GLP-1R agonists 45