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J Biol Chem 265:1291612926 Richards EM, Rosenthal RE, Kristian T, Fiskum G (2006) Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity

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S5B) [33, 34]

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This makes NNMT directly relevant to nicotinamide metabolism, NAD + salvage biology, and methyl-donor balance

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